Ciro Santilli $£ Sponsor €¥ 中国独裁统治 China Dictatorship 新疆改造中心、六四事件、法轮功、郝海东、709大抓捕、2015巴拿马文件 邓家贵、低端人口、西藏骚乱
Genome:
  • 3 Gbps
  • 20k genes
  • 37.2 trillion cells[ref]
www.ncbi.nlm.nih.gov/projects/genome/guide/human/index.shtml
wget ftp://ftp.ncbi.nlm.nih.gov/refseq/H_sapiens/annotation/GRCh38_latest/refseq_identifiers/GRCh38_latest_genomic.fna.gz
gunzip --keep GRCh38_latest_genomic.fna.gz

Human body

split words: 202
www.humancellatlas.org/
The point of these is that they are good for transfection apparently.
20k genes, 3 billion base pairs. We can handle this!!!
This is really cool. Ciro Santilli would be tempted to participate, but his wife is not a fan, in part due to the loss of privacy of children. Maybe she is right...
Someone should implement a version of that where you can upload your privately sequenced genome and get analytics for free.
This was the first large part of the genome that was sequenced, in 1981: Cambridge Reference Sequence. Presumably they picked it because it is short and does not undergo crossover.
About 16.6 kbp:
TODO: many places say "exactly" 16,569, it seems that variable number tandem repeat are either rare or don't occur!
By Fred Sanger's group.
Published as: sequence and organization of the human mitochondrial genome by Sanger et al. (1981).
www.nature.com/articles/290457a0
As mentioned by Craig Venter in 100 Greatest Discoveries by the Discovery Channel (2004-2005), the main outcomes of the project were:
  • it established the ballpark number of human genes
  • showed that human genomes are very similar across individuals.
Important predecessors:
This was one of the first notable country-led large scale sequencing efforts of the world.
Sample paper: www.nature.com/articles/ng.3247
UniProt human: www.uniprot.org/uniprot/Q9BYF1 It is interesting to see in the Mutagenesis how many known mutations can increase or decrease SARS-CoV-2 S protein binding affinity.
Receptor in SARS-CoV-2 cell entry.
Receptor in SARS-CoV-2 cell entry.

Human body system

split

Tagged

Ancestors

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