You can connect form an Ubuntu 22.04 host as:
screen /dev/ttyACM0 115200
screen, you can Ctrl + C to kill
main.py, and then execution stops and you are left in a Python shell. From there:
but be aware of: Raspberry Pi Pico W freezes a few seconds after after screen disconnects from UART.
- Ctrl + D: reboots
- Ctrl + A K: kills the GNU screen window. Execution continues normally
runcommand, which solves How to run a MicroPython script from a file on the Raspberry Pi Pico W from the command line?