- prokaryote models:
- E. Coli: the most well studied
- mycoplasma: a very minimal genus, notable species: Mycoplasma genitalium
- eukaryote
- S. cerevisiae: simplest eukaryote model. Unicellular.
- C. elegans: simplest multicellular organism model
- vertebrate:
- Zebrafish: simplest vertebrate model
- mammal:
- Mus musculus: simplest mammal model